Immobilization of biologically active substances on a carrier co

Details Immobilization of biologically active substances on a carrier co Immobilization of biologically active substances on a carrier co

1998-01-20

2000-01-25

Naff, David M.

Chemistry: molecular biology and microbiology

Carrier-bound or immobilized enzyme or microbial cell;...

Enzyme or microbial cell is immobilized on or in an organic...

435174, 435177, 435181, 436524, 436528, 436531, 436532, 530811, 530812, 530815, 530816, C12N 1108, G01N 33545, C07K 1708

Patent

active

06017742&

ABSTRACT:
A material is provided for immobilization of biologically active substances which are reactive with a carbodiimide group. The material contains a carbodiimide group-containing polymer supported on a carrier such as a plastic, an inorganic polymer, a metal, a natural polymer or a ceramic. The carbodiimide group-containing polymer has 2 to 100 carbodiimide groups per molecule and a molecular weight of 1,000 to 100,000, and is prepared by carbodiimidization of an organic polyisocyanate in the presence of a catalyst. The polymer may be supported as a film on part or the whole area of the carrier. Biologically active substances that may be immobilized include enzymes, hormones, antibodies, antigens, heptenes, peptides, DNAs and RNAs.

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patent: 5079326 (1992-01-01), Suzuki et al.
patent: 5373080 (1994-12-01), Imashiro et al.
Oskar Zaborsky; "Immobilized Enzymes"; CRC Press; 1973; pp. 26-27.

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