Immobilization of biologically active material with glutaraldehy

Details Immobilization of biologically active material with glutaraldehy Immobilization of biologically active material with glutaraldehy

1988-06-30

1990-01-09

Naff, David M.

Chemistry: molecular biology and microbiology

Carrier-bound or immobilized enzyme or microbial cell;...

Enzyme or microbial cell is immobilized on or in an organic...

435177, 435182, C12N 1108, C12N 1102, C12N 1104

Patent

active

048928259

ABSTRACT:
Immobilized biologically active material in particle form is prepared by cross-linking with glutaraldehyde and polyazetidine. An aqueous dispersion or solution of biologically active material is partially cross-linked with glutaraldehyde, a wet pasty mass is recovered by dewatering and the mass is sub-divided into discrete particles. A polyazetidine prepolymer is added before, at the beginning or subsequent to partially cross-linking but prior to subdividing the pasty mass into particles, and the prepolymer is allowed to cross-link.

REFERENCES:
patent: 3779869 (1973-12-01), Zienty
patent: 3974036 (1976-08-01), Snell
patent: 3980521 (1976-09-01), Amotz et al.
patent: 4288552 (1981-09-01), Gestrelius
patent: 4355105 (1982-10-01), Lantero, Jr.
patent: 4436813 (1984-03-01), Wood et al.
patent: 4600692 (1986-07-01), Wood et al.

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