Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an organic...
Patent
1983-12-29
1986-04-15
Naff, David M.
Chemistry: molecular biology and microbiology
Carrier-bound or immobilized enzyme or microbial cell;...
Enzyme or microbial cell is immobilized on or in an organic...
435177, 435181, C12N 1108, C12N 1102, C12N 1106
Patent
active
045828059
ABSTRACT:
A process is disclosed for the chemical immobilization of biological material such as bacteria and enzymes containing an active hydrogen with a vinyl addition polymer of an isocyanatoalkyl ester of an ethylenically unsaturated carboxylic acid. The vinyl addition polymer is versatile in that it can be copolymerized with varying amounts and types of comonomers.
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Fusee et al., "Immobilization of Escherichia coli Cells Containing Aspartase Activity with Polyurethane and its Application for L-Aspartic Acid Production", Applied and Environmental Microbiology, Oct. 1981, pp. 672-676.
Sonomoto et al., "Application of Urethane Prepolymers to Immobilization of Biocatalysts: .DELTA.-Dehydrogenation of Hydrocortisone by Arthrobacter Simplex Cells Entrapped with Urethane Prepolymers", Agri. Biol. Chem. 44(5), 1119-1126, (1980).
Goldstein, "Chemically Modified Polymers Containing Isocyanide Functional Groups as Supports for Enzyme Immobilization", Biotech. Applns of Proteins and Enzymes, Acad. Press NY, 1977, pp. 153-167.
Bozzelli John W.
Cheng Roberta C.
Corneglio, Jr. Donald L
Naff David M.
The Dow Chemical Company
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