Immobilization of biological cells in polytetrafluoroethylene ma

Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an organic...

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435174, 435177, 435180, C12N 1104, C12N 1102, C12N 1108

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active

047228989

ABSTRACT:
A polytetrafluoroethylene (PTFE) fibril matrix is prepared containing entrapped viable cells such as animal, bacterial, fungal or yeast cells. Cells are blended with surfactant and soap-free PTFE in aqueous dispersion to form a damp paste. Water is added to the paste and a resultant stiff dough is biaxially calendered between calendering rolls to cause fibrillation and form the PTFE fibril matrix. Calendering is preferably carried out at a temperature of 5.degree. to 70.degree. C. and a pressure of 1000 to 3000 MPa. The fibril matrix may be dried.

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