Immobilization of biocatalysts on granular diatomaceous earth

Details Immobilization of biocatalysts on granular diatomaceous earth Immobilization of biocatalysts on granular diatomaceous earth

1985-09-23

1987-12-15

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435176, C12P 1920, C12N 1114

Patent

active

047133333

ABSTRACT:
Disclosed is a process whereby enzymes are immobilized on granular diatomaceous earth. The process involves treating the diatomaceous earth with a polyamine compound having pendant amino groups to cause the polyamine to adhere to the diatomaceous earth leaving pendant amine groups free to react further. The free amine groups are derivatized by treatment with a difunctional compound having amine reactive moieties, so that free amine groups of an enzyme or enzymes can be covalently bound to the polyamine via the amine reactive compound.

REFERENCES:
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patent: 4141857 (1979-02-01), Levy et al.
patent: 4292199 (1981-09-01), Rohrbach et al.
patent: 4438196 (1984-03-01), Lantero, Jr.
patent: 4581338 (1986-04-01), Robertson et al.
patent: 4665028 (1987-05-01), Amotz
Derwent Abstract, 80941A/45 of Japanese Pat. No. 53-113082, (Oct. 1978).

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