Immobilization of active protein by cross-linking to inactive pr

Details Immobilization of active protein by cross-linking to inactive pr Immobilization of active protein by cross-linking to inactive pr

1985-09-13

1990-11-13

Naff, David M.

Chemistry: molecular biology and microbiology

Carrier-bound or immobilized enzyme or microbial cell;...

435176, 435177, 435178, 435179, 435180, 436518, 436519, 436524, 436528, 436529, 436530, 436531, 530810, 530811, 530812, 530814, 530815, C12N 1100, C12N 1102, G01N 33543, G01N 33544

Patent

active

049701568

ABSTRACT:
A solution of an active protein substance and an inactive protein substance is reacted with a cross-linking agent, optionally in the presence of an inert carrier, under cross-linking conditions to produce articles comprising both active and inactive protein substances. The active protein substance comprises up to about 20 percent, e.g. from 1 to 20 percent by weight, based on the final weight of the total protein substance, whereas the cross-linking agent comprises from 0.5 to 8 percent by weight, based on the weight of the total treated mixture. The obtained articles are in the form of a solution or a suspension in aqueous medium, in the form of a film, in the form of a membrane, in the form of a fabric, in the form of a porous material, or in the form of a mass, such as granules, pills or tablets.

REFERENCES:
patent: 3639558 (1972-02-01), Csizmas et al.
patent: 4004979 (1977-01-01), Aurameas et al.
patent: 4464468 (1984-08-01), Aurameas et al.
Sabatini, et al., The Journal of Cell Biology, vol. 17, 1963 (pp. 19-58).
Schick et al., The Journal of Biological Chemistry, vol. 236, 1961 (pp. 2477-2485).
Silman, et al., Biopolymers, vol. 4, 1966 (pp. 441-448).
Aurameas, et al., Journal of Biological Chemistry, vol. 242, No. 7, 1967 (pp. 1651-1659).
Habeeb, A. F. S. A., Archives of Biochemistry and Biophysics, vol. 119, 1967 (pp. 264-268).
Quiocho, et al., Proc., Natl. Accd. Sci., U.S., vol. 52, 1964 (pp. 833-839).
Clinca Chimica Acta, Romette, 19, 249-253, (1979).
Hackh's Chemical Dictionary, 4th Edition, page 293, McGraw-Hill Book Company, 1969.

Affiliated with

Also associated with

Rating

Immobilization of active protein by cross-linking to inactive pr does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Immobilization of active protein by cross-linking to inactive pr, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Immobilization of active protein by cross-linking to inactive pr will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-776575