Immobilization of acid-treated antibodies on siliceous support

Chemistry: analytical and immunological testing – Involving production or treatment of antibody

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Details

435 794, 435 792, 435 71, 5303871, 5303891, G01N 3353, C07K 1600

Patent

active

058693491

ABSTRACT:
The antigen-binding activity of an antibody immobilized on a siliceous support can be increased by pretreatment of the antibody with acid prior to its immobilization.

REFERENCES:
patent: 3652761 (1972-03-01), Weetall
patent: 4071409 (1978-01-01), Messing et al.
patent: 5073485 (1991-12-01), Amano et al.
Ishikawa, et al., J. Immunoassay, 1(3):385-398, 1980.
Conrdie, et al., JIM, 59:289-299, 1983.
Lin et al., JIM, 125:67-77, 1989.

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