Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;...
Reexamination Certificate
2006-04-11
2009-08-18
Kam, Chih-Min (Department: 1656)
Chemistry: molecular biology and microbiology
Carrier-bound or immobilized enzyme or microbial cell;...
C530S395000, C530S350000
Reexamination Certificate
active
07575908
ABSTRACT:
A method and kit for immobilization of a glycoprotein. The method may include activating an affinity support. The affinity support may be activated by reacting the affinity support with a compound that is reactive with one or more functional groups included within the glycoprotein. The method may also include oxidizing the glycoprotein in which oxidation conditions are selected to yield an oxidized glycoprotein that is biologically active and contains a sufficient number of reactive aldehyde groups for coupling to a support. For example, the oxidized glycoprotein may include five reactive aldehyde groups. In addition, the method may include reacting the oxidized-glycoprotein with the activated affinity support to immobilize the glycoprotein.
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Hage David S.
Xuan Hai
Board of Regents of the University of Nebraska
Kam Chih-Min
Romano Charles P.
Thompson & Coburn LLP
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