Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...
Patent
1996-10-10
1999-09-07
Mosher, Marv E.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
4353201, 4352523, 43525411, 435419, 435 5, 435 6, 435 691, 435 693, 4352351, 536 2372, 536 2432, C12N 1500, C12N 1509
Patent
active
059486767
ABSTRACT:
This invention provides an isolated nucleic acid molecule which encodes Kaposi's Sarcoma-Associated Herpesvirus (KSHV) immediate early protein (IEP). This invention provides an isolated polypeptide molecule which encodes KSHV immediate early protein. This invention provides an antibody specific to the polypeptide. Antisense and triplex oligonucleotide molecules are also provided. This invention provides a vaccine for Kaposi's Sarcoma (KS). This invention provides methods of vaccination, prophylaxis, diagnosis and treatment of a subject with KS and of detecting expression of a DNA virus associated with Kaposi's sarcoma in a cell.
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Bohenzky Roy A.
Chang Yuan
Edelman Isidore S.
Moore Patrick S.
Russo James J.
Mosher Marv E.
Salimi Ali R.
The Trustees of Columbia University in the City of New York
White John P.
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