Imipramine derivatives and poly(amino acid) conjugates

Details Imipramine derivatives and poly(amino acid) conjugates Imipramine derivatives and poly(amino acid) conjugates

1979-07-06

1981-06-23

Schain, Howard E.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Stablizing an enzyme by forming a mixture, an adduct or a...

260112R, 260112B, 260121, 260239BB, 424 85, 424 88, 435 7, 525420, C07G 700, C12N 996

Patent

active

042751608

ABSTRACT:
Imipramine functionalized compounds are provided for conjugation to antigenic compounds, particularly poly(amino acids), and enzymes. The antigenic conjugates are employed for the production of antibodies, which find particular use in immunoassays for the determination of imipramine, while the enzyme conjugate finds use in a homogeneous enzyme assay for the determination of imipramine.

REFERENCES:
patent: 4058511 (1977-11-01), Singh
patent: 4083948 (1978-04-01), Davis et al.
patent: 4104379 (1978-08-01), Gallagher, Jr. et al.
J. Anal. Tox. 1, pp. 236-243, (1977), Kaul et al.

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