Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1994-06-15
1996-05-28
Chan, Christina Y.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530385, A61K 3800, C07K 14805
Patent
active
055211542
ABSTRACT:
An imidoester, cross-linked hemoglobin composition useful in the transport of oxygen to living cells and being essentially free of any impurities, a P50 of at least 13mm Hg and predominantly in tetraruer form. Preferably, the cross-linked hemoglobin composition has a predominant molecular weight of at least 64,000. The purified and cross-linked hemoglobin has improved cross-link stability to autoxidation and can be used as a blood substitute for mammals or as an oxygen transport fluid.
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Garlick Robert L.
Lyle Stephen B.
Martin, Jr. Joseph P.
Chan Christina Y.
Corneglio Donald L.
The Upjohn Company
Touzeau P. Lynn
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