Imidazopyridinones as p38 map kinase inhibitors

Details Imidazopyridinones as p38 map kinase inhibitors Imidazopyridinones as p38 map kinase inhibitors

2006-01-10

2006-01-10

Huang, Evelyn Mei (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S300000, C514S303000, C546S086000, C546S084000, C546S117000, C546S121000

Reexamination Certificate

active

06984646

ABSTRACT:
The invention relates to imidazopyridinones of the formulawherein the groups R1, R2, R3, and R4are as defined in claim 1, to the process for their preparation, to pharmaceutical compositions containing them, and to a method of using them for treatment of chronic inflammatory processes in humans or animals.

REFERENCES:
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patent: 5585595 (1980-06-01), None
Liverton et al. J. Med. Chem. 1999, 42: 2180-21.
Chem. Abstracts, 1981: 47326 HCAPLUS.
Darwent Abstracts, 1980-57588C [33] WPIDS.
Japanese Patent Abstracts, 1980-085595 JAPIO.
Kubo, et al., Studies on the Synthesis of 2(1H)-Pyridone Derivatives, IV. Synthesis of Condensed Heterocyclic 2(1H)-Pyridones, UDC, 99, 880-888, (1979).
Knolker, et al., Imidazole Derivatives. Part II, Synthesis of Imidazo [1,2-a] Pyridin-5-Ones, Heterocycles, 29, 1551-1558, (1989).
Hiroshige, Novel Heterocyclic Compound, Pat. Abstracts of Japan, vol. 004, JP 55 085595 (1980).

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