Imidazopyridazines, their production and use

Details Imidazopyridazines, their production and use Imidazopyridazines, their production and use

1994-11-21

1996-02-13

Bernhardt, Emily

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544117, 544232, 544234, 544236, 544383, 558 12, 560125, 560150, 560226, 560266, 564 95, 568613, 568681, A61K 3150, C07D48704

Patent

active

054911451

ABSTRACT:
Novel compound of the general formula: ##STR1## wherein R.sup.1 stands for a hydrogen atom, an optionally substituted lower alkyl group or a halogen atom; R.sup.2 and R.sup.3 respectively stand for a hydrogen atom or an optionally substituted lower alkyl group, provided that either R.sup.2 or R.sup.3 is a hydrogen atom, the other being an optionally substituted lower alkyl group, or R.sup.2 and R.sup.3 may, taken together with the adjacent --C=C-- group, form a 5- to 7-membered ring; X stands for an oxygen atom or S(O).sub.p (p stands for an integer from 0 to 2; Y stands for a group of the formula: ##STR2## (R.sup.4 and R.sup.5 respectively stand for a hydrogen atom or an optionally substituted lower alkyl group) or a divalent group derived from an optionally substituted 3- to 7-membered homocyclic or heterocyclic ring; R.sup.6 and R.sup.7 each stands for a hydrogen atom, an optionally substituted lower lakyl group, an optionally substituted cycloalkyl group or an optionally substituted aryl group, or R.sup.6 and R.sup.7 may, taken together with the adjacent nitrogen atom, form an optionally substituted nitrogen-containing heterocyclic group; m stands for an integer from 0 to 4; and n stands for an integer from 0 to 4, or a salt thereof, which has excellent anti-PAF activities, and is of value as an antiasthmatic agent, and their production, intermediates and pharmaceutical compositions.

REFERENCES:
patent: 5145850 (1992-09-01), Miyake et al.
patent: 5155108 (1992-10-01), Miyake et al.
patent: 5202324 (1993-04-01), Miyake et al.

Affiliated with

Also associated with

Rating

Imidazopyridazines, their production and use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Imidazopyridazines, their production and use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Imidazopyridazines, their production and use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-240738