Imidazopyridazines, their production and use

Details Imidazopyridazines, their production and use Imidazopyridazines, their production and use

1991-02-25

1992-09-08

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514210, 514218, 5142285, 5142332, 540575, 540599, 544 61, 544117, 544236, 549426, 549497, 549511, 558 15, 558 16, 560250, 564 80, A61K 3150, A61K 31535, A61K 3155, C07D48704

Patent

active

051458500

ABSTRACT:
An imidazo [1,2-b]pyridazine compound of the formula (I): ##STR1## wherein R.sub.1 is a halogen atom or a lower alkyl group optionally having substituent(s), R.sub.2 and R.sub.3 are, independently, a hydrogen atom, a lower alkyl group optionally having substituent(s), a cycloalkyl group or a phenyl group optionally having substituent(s) or R.sub.2 and R.sub.3 together with the adjacent nitrogen atom to which they bond may form a heterolcyclic ring optionally having substituent(s), X is an oxygen atom or S(O).sub.k (k is zero to two), a group --.circle.A-- is a bivalent three to seven membered homocyclic or heterocyclic group optionally having substituent(s), m.sup.1 and m.sup.2 each is an integer of 0 to 4 and n is an integer of 0 or 1; or its salt, which is useful as antiasthmatics.

REFERENCES:
patent: 4464372 (1984-08-01), Bristol et al.
Miyake et al, Chemical Abstracts, vol. 114, No. 102028 (1990) (Abstract for EP 381132).
Abstract for JP 01040489 (Feb. 10, 1989).

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