Imidazopyrazines as cyclin dependent kinase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S295000, C544S350000

Reexamination Certificate

active

07576085

ABSTRACT:
In its many embodiments, the present invention provides a novel class of imidazo[1,2-a]pyrazine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions. An illustrative compound of the invention is shown below:

REFERENCES:
patent: 6919341 (2005-07-01), Paruch et al.
patent: 2007/0117804 (2007-05-01), Zhao et al.
Vippagunta et. al. Advanced Drug Delivery Reviews 48 (2001) 3-26.
Dorwald F. A. Side Reactions in Organic Synthesis, 2005, Wiley: VCH, Weinheim p. IX of Preface.

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