Imidazolylphenyl amidines, pharmaceutical compositions containin

Details Imidazolylphenyl amidines, pharmaceutical compositions containin Imidazolylphenyl amidines, pharmaceutical compositions containin

1981-11-19

1983-05-31

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

424272, 548245, 548336, 548346, A61K 31415, C07D23364

Patent

active

043860990

ABSTRACT:
This invention relates to imidazolylphenyl amidines, the preparation thereof, and pharmaceutical compositions containing them. More particularly, this invention relates to compounds of the general formula ##STR1## in which R, R.sub.1, R.sub.3, which may be the same or different, each represent a hydrogen atom or a lower alkyl group, and R.sub.2 represents a linear or branched alkyl, alkenyl, or alkynyl group, a cyano group, a hydroxyl group, a substituted or unsubstituted cycloalkyl or cycloaliphatic alkyl group, a bicyclic group, an aralkyl or aryl group optionally substituted by halogen, methyl, methoxy, or methylenedioxy groups, or a substituted or unsubstituted heterocyclylalkyl or heterocyclic group which may also contain a further hetero atom, or a non-toxic, pharmacologically acceptable acid addition salt thereof. These compounds are useful in treating disorders of the gastrointestinal tract.

REFERENCES:
patent: 4225724 (1980-09-01), Warner et al.

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