Imidazolyl-oxime ethers having anti-mycotic and bactericidal act

Details Imidazolyl-oxime ethers having anti-mycotic and bactericidal act Imidazolyl-oxime ethers having anti-mycotic and bactericidal act

1976-12-27

1978-11-07

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424273R, C07D23360

Patent

active

041247671

ABSTRACT:
Imidazolyl oxime ethers (I) are disclosed which contain an aromatic or heteroaromatic grouping linked to the carbon atom of the oxime ether, the oxime being etherified by a variety of groups; aliphatic, aromatic, heteroaromatic, cycloaliphatic and aliphatic substituted by aromatic, heteroaromatic or cycloaliphatic groups. The compounds are obtained from the corresponding ketones by reaction with O-substituted hydroxylamines or by reaction of metal oximates with halides of the required etherifying group. The said products (I) possess antimycotic and bactericidal activity.

REFERENCES:
patent: 3515728 (1970-06-01), Henry et al.
patent: 3818029 (1974-06-01), Regel et al.
patent: 3951963 (1976-04-01), Winkelmann et al.
Godefroi et al., J. Med. Chem., 1969, vol. 12, pp. 784-791.

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