Imidazolyl alkyl guanidine derivatives, processes for their prep

Details Imidazolyl alkyl guanidine derivatives, processes for their prep Imidazolyl alkyl guanidine derivatives, processes for their prep

1989-02-28

1991-06-04

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514341, 514397, 514400, 546256, 546278, 548336, 548342, A61K 3144, A61K 31415, A61K 3138, C07D40313

Patent

active

050214314

ABSTRACT:
New imidazolylalkyl-guanidine derivatives are described, which by virtue of their agonistic action on histamine-H.sub.2 receptors and in part also due to their additional H.sub.1 -antagonistic receptor activity can be used in the treatment of cardiac diseases, certain forms of hypertension and diseases of arterial occlusion.
These imidazolylalkyl-guanidine derivatives correspond to the general formula I: ##STR1##

REFERENCES:
patent: Re29761 (1978-09-01), Durant et al.
patent: 3736331 (1973-05-01), Black et al.
patent: 4048319 (1977-09-01), Black et al.
patent: 4098898 (1978-07-01), Durant et al.
patent: 4109003 (1978-08-01), Durant et al.
patent: 4912119 (1990-03-01), Buschauer et al.

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