Imidazolyl alkyl bisamidines

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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548337, 548342, 548301, 546300, 546305, 546306, 546332, 424263, 424269, 424270, 424272, 548136, 548262, C07D23364, C07D23366, A61K 31415

Patent

active

042128757

ABSTRACT:
Bisamidines carrying one unsaturated nitrogen heterocycle-containing substituent, representative of which is 1-[N'-(2-(5-methyl-4-imidazolyl)methylthio)ethyl)guanidino]-8-[N'-methyl-g uanidino]octane, are histamine H.sub.2 -antagonists.

REFERENCES:
patent: 4034101 (1977-07-01), Durant et al.
patent: 4062967 (1977-12-01), Durant et al.

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