Imidazolyl-3,5-di-(diphenyl-butylsilyloxy) carboxylic acid ester

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D 718

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active

047556064

ABSTRACT:
Compounds of the formula ##STR1## and the pharmaceutically acceptable acid addition salts thereof, wherein the various substituents are defined herein below,
the use thereof for inhibiting cholesterol biosynthesis and lowering the blood cholesterol level and, therefore, in the treatment of hyperlipoproteinemia and atherosclerosis, pharmaceutical compositions comprising such compounds and processes for and intermediates in the synthesis of such compounds.

REFERENCES:
patent: 4028343 (1977-06-01), Amort et al.
patent: 4530922 (1985-07-01), Moberg
patent: 4650890 (1987-03-01), Jewell et al.
patent: 4677211 (1987-06-01), Jewell et al.

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