Imidazolone anorectic agents: III. heteroaryl derivatives

Details Imidazolone anorectic agents: III. heteroaryl derivatives Imidazolone anorectic agents: III. heteroaryl derivatives

Filed on

1999-03-03

Date issued

2000-08-01

Examiner

Shah, Mukund J.

Patent Class

Drug, bio-affecting and body treating compositions

SubClass

Designated organic active ingredient containing

SubSubClass

Heterocyclic carbon compounds containing a hetero ring...

Other Related Categories

514256, 514341, 514380, 5142521, 544333, 544405, 5462741, 5462744, 548260, 5483124, 5483147, 5483151, 5483157, A61K 314166, C07D23370, C07D23924, C07D24110

Type

Patent

Status

active

Patent number

060967455

Description

ABSTRACT:
A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of heteroaryl derivatives of imidazolone compounds of Formula 1. ##STR1## As antagonists of NPY-induced feeding behavior, these compounds and known analogs are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.

REFERENCES:
patent: 3894008 (1975-07-01), Irvine
Gehlert, et al., "Neuropeptide Y Receptor Antagonists in Obesity," Expert Opinion on Investigational Drugs, vol. 6, No. 12, Dec. 1997, pp. 1827-1838 .

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