Imidazolone anorectic agents: 1. 2-substituted-3,5-dihydro-5,5-d

Details Imidazolone anorectic agents: 1. 2-substituted-3,5-dihydro-5,5-d Imidazolone anorectic agents: 1. 2-substituted-3,5-dihydro-5,5-d

1999-03-03

2000-05-16

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514398, 5483255, C07D23330, C07D23332, C07D23370, A61K 31415

Patent

active

060639342

ABSTRACT:
A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of acyclic derivatives of imidazolone compounds of Formula I. ##STR1## As antagonists of NPY-induced feeding behavior, these compounds and known analogs are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.

REFERENCES:
patent: 2744852 (1956-05-01), Goodman
patent: 2902356 (1959-09-01), Luckenbaugh et al.
patent: 4280008 (1981-07-01), Schoellkopf et al.
patent: 4304782 (1981-12-01), Dumont et al.
patent: 5213607 (1993-05-01), Guaciaro
Gehlert, et al., "Neuropeptide Y Receptor Antagonsts in Obesity," Expert Opinion on Investigational Drugs, vol. 6, No. 12, Dec. 1977, pp. 1827-1838 .

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