Imidazolinylmethyl aralkylsulfonamides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S355100

Reexamination Certificate

active

07407980

ABSTRACT:
Compounds of the Formula:where R1-R6are those defined herein and methods for producing the same. Also provided are pharmaceutical compositions comprising a Compound of Formula I and methods for their use as therapeutic agents.

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Thompson et al., Current Medicinal Chemistry, Oct. 2002, 9(19), pp. 1751-1762.
Nardi, D., et al., Hypertensive Activity of 2-(2,3,4,6-tetramethylbenzyl) imidazoline and related compounds, (Research on Durene Derivatives),Farmaco., Ed. Sci. (1979) pp. 789-801, vol. 34(9).
Lis, R., et al., “Synthesis and Antiarrhythmic Activity of Novel 3-Alkyl-1-[w-[4-[(alkylsulfonyl)amino]phenyl]-w-hydroxyalkyl]-1H -imidazolium Salts and Related Compounds,”J. Med. Chem., (1987), pp. 2303-2309, vol. 30.
Mashkovski, M. D. Arzneimittel Handbuch für Aerzte, Teil I, Moskau, 1993, pp. 8.

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