Imidazolinone resistant AHAS mutants

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses

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4351721, 435183, 4353201, 435 6, 435 76, 4352401, 4352404, 4352523, 435 691, 435 701, 435 711, 536 232, 536 236, 530376, C12N 1563, C12N 1529, C12N 510, C12N 121

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057311803

ABSTRACT:
The present invention relates to monocot genes encoding a mutant AHAS enzyme that is specifically resistant to imidazolinone herbicides. Exemplary of these genes are corn DNA sequences which encode an amino acid substitution at position 621 of the wild-type AHAS enzyme. The mutant gene can be used to transform other plants to herbicide resistance; in this regard, the invention also provides host cells and vectors containing the gene, which cells and vectors are useful in the transformation process.

REFERENCES:
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Jen et al. (Abstract) J. Cellular Biochem., vol. 14E (supplement) (1990) p. 302.
Wiersma et al. Mol. Gen. Genet., vol. 219 (1989) pp. 413-420.
Lesser, W.H., ed., Animal Patents, N.Y., Stockton Press, 1989, p. 159.
Haughn, G. et al., "A mutation causing imidazolinone resistance . . . " Plant Physiology, vol. 92, (Apr., 1990), pp. 1081-1085.
Sathasivan et al., "Nucleotide sequence of a mutant acetolacrane synthase gene . . . ", Nucleic Acids Research, vol. 18 (Apr. 1990) p. 2188.
Haughn et al., "Transformatioin with a mutant Arabidopsis acetoacetate synthease gene . . . ", Mol. Gen. Genet., vol. 211 (1988) pp. 266-271.

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