Imidazoline derivatives and the preparation thereof

Details Imidazoline derivatives and the preparation thereof Imidazoline derivatives and the preparation thereof

1975-04-07

1976-10-26

Love, Ethel G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603097, 424273, C07D 4934

Patent

active

039883450

ABSTRACT:
A process for the preparation of 2-(substituted aryl)amino-2-imidazoline derivatives by reacting appropriate substituted aniline derivatives with 1-aroyl-imidazoline-2-ones in the presence of at least two mols of phosphorus oxychloride per mol of the aniline derivative and optionally hydrolyzing the resulting intermediate compound. Certain novel 2-dihaloarylamino-2-imidazoline derivatives with hypotensive action are also disclosed.

REFERENCES:
patent: 3931216 (1976-01-01), Franzmair
Najer et al., Bull'n Soc. Chim. France, 1961, pp. 2114-2126.

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