Imidazoline derivative and method of treating depression therewi

Details Imidazoline derivative and method of treating depression therewi Imidazoline derivative and method of treating depression therewi

1981-02-02

1989-04-04

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548348, A61K 31415, C07D40300

Patent

active

048187640

ABSTRACT:
2-[2-(1,4-Benzodioxanyl)]-2-imidazoline or a non-toxic salt thereof, substantially free of 2-[2-(2-methyl-1,3-benzodioxyl)]- 2-imidazoline or a non-toxic salt thereof.
2-[2-(1,4-Benzodioxanyl)]-2-imidazoline or a non-toxic salt thereof characterised in that the nuclear magnetic resonance spectrum of the compound in a protonated form exhibits multiplets in the region of .tau.4.4 and .tau.5.4.
Process for the preparation of 2-[2-(1,4-benzodioxanyl)]-2-imidazoline, pharmaceutical compositions thereof or of its salts, and their use as presynaptic .alpha..sub.2 -adrenoreceptor antagonists.

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