Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-10-04
1991-09-24
Ford, John M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548353, C07D23320, A61K 31415
Patent
active
050514415
ABSTRACT:
Imidazoline derivative of the formula: ##STR1## wherein R is a halogenophenyl group or a pyridyl group and X.sup.1 and X.sup.2 are a hydrogen atom or a lower alkoxy group, or a pharmaceutically acceptable salt thereof, which is useful as an immunomodulator and as an agent for the treatment and/or prophylaxis of rheumathoid arthritis, multiple sclerosis, systemic lupus erythemathodes, rheumatic fever and the like, a process for the preparation thereof, and a pharmaceutical composition containing said compound as an active ingredient.
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Merck Index, 9th Edition, p. 51 (1976).
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Hunter et al., Canadian Journal of Chemistry, vol. 50 (1972), pp. 669-677.
Zupanc et al., Bull. Soc. Chem. & Technolog., Sarajevo (Yugoslavia), 27/28 (1980-1981), pp. 71-80.
Iwasawa Yoshio
Matsumoto Kazuo
Suzuki Mamoru
Takata Isao
Yamamoto Kozo
Ford John M.
Tanabe Seiyaku Co. Ltd.
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