Imidazoline compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

5483471, 5483481, 5483491, 5483511, 5483531, 5483541, A61K 31415, C07D23364

Patent

active

059256656

ABSTRACT:
Compound of formula (I): in which R is as defined in the description, as well as their isomers and their pharmaceutically acceptable acid additions salts. Medicinal products containing the same are useful as Imidazoline receptors ligand.

REFERENCES:
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patent: 4910206 (1990-03-01), Houlihan, I
patent: 5154858 (1992-10-01), Wakita et al.
Wagner et al "Agents for Affecting the Rheological, etc" CA 89: 113808 (1978).
Levesque et al, "4,5-Dihydorimidazoles from, etc" CA 96:122690 (1982).
Keem et al, "Dehydrogenation of 2-aryl-2-, etc" CA 72: 121439 (1970).
A. Schulz et al., "Dual action of clonidine on insulin release: suppression, but stimulation when .alpha..sub.2 -adrenoceptors are blocked", Naunya-Schmiedeberg's Arch Pharmocal (1989) 340: 712-714.
R. E. Klem et al., "Dehydrogenation of 2-Aryl-2-imidazolines with Selenium"Notes XP-002058798, Apr. 1970, p. 403.

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