Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent
Patent
1977-03-15
1978-07-04
Daus, Donald G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Chalcogen in the nitrogen containing substituent
544 21, 2603322A, 548319, 548318, 560 32, C07D50136
Patent
active
040990010
ABSTRACT:
[[[Imidazolidinyl amino]carbonyl]amino]acetylcephalosporin derivatives having the formula ##STR1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, diphenyl-lower alkyl, tri(lower alkyl)silyl, trihaloethyl, a salt forming ion, or the group ##STR2## R.sub.1 is hydrogen or methoxy; R.sub.2, R.sub.3 and R.sub.5 each is hydrogen or lower alkyl; R.sub.4 is hydrogen, lower alkyl, cyclo-lower alkyl, cyclo-lower alkenyl, cyclo-lower alkadienyl, phenyl, phenyl-lower alkyl, substituted phenyl, substituted phenyl-lower alkyl, or certain heterocyclic groups; R.sub.6 is lower alkyl; and X is hydrogen, lower alkanoyloxy, ##STR3## or certain heterothio groups; are useful as antibacterial agents.
REFERENCES:
patent: 3687641 (1972-08-01), Holdrege
patent: 3833568 (1974-09-01), Dolfini et al.
patent: 3954802 (1976-05-01), Kocsis
patent: 4028354 (1977-06-01), Breuer et al.
Breuer Hermann
Treuner Uwe D.
Daus Donald G.
E. R. Squibb & Sons Inc.
Levinson Lawrence S.
Smith Merle J.
Wheeler David E.
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