Imidazoles useful as antiatherosclerotic agents

Details Imidazoles useful as antiatherosclerotic agents Imidazoles useful as antiatherosclerotic agents

1990-09-27

1992-04-07

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548336, A61K 31415, C07D40504

Patent

active

051029006

ABSTRACT:
Imidazole derivatives of the formula: ##STR1## are described wherein R.sup.1 represents halogen, alkyl or alkoxy, n is 0 to 5, R.sup.2 represents hydrogen or alkyl, R.sup.3 represents hydrogen or alkyl optionally substituted by halogen, hydroxy, acyloxy, alkoxy, hydroxyalkoxy, acyloxyalkoxy, or by optionally substituted phenyl, or the groups R.sup.3 and the carbon atom to which they are attached together form a cycloalkane or cycloalkene group. They are pharmaceutically useful as antiatherosclerotic agents.

REFERENCES:
patent: 4315021 (1982-02-01), Kluge et al.
patent: 4992421 (1991-02-01), De et al.
patent: 4992457 (1991-02-01), Schulman et al.

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