Imidazole derivatives or salts thereof and drugs containing...

Details Imidazole derivatives or salts thereof and drugs containing... Imidazole derivatives or salts thereof and drugs containing...

2005-10-25

2005-10-25

Balasubramanian, Venkataraman (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S272700, C544S405000, C514S255050

Reexamination Certificate

active

06958353

ABSTRACT:
The invention is directed to an imidazole derivative represented by formula (1):wherein each of R1and R2represents an aryl group, a heteroaryl group, etc.; each of A, X1, and X2represents N or CH; each of Y and Z represents O, S, etc.; each of R3, R4, and R5represents a hydrogen atom, an alkyl group, etc.; m is a number of 1 to 4; and n is a number of 0 to 4, or a salt thereof. The invention is also directed to a drug containing the derivative or the salt as an active ingredient. These compounds exert excellent effects of inhibiting production of NO and IL-6 and are useful for preventing or treating diseases induced by overproduction of NO and IL-6.

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