Imidazole derivatives and use as anti-bacteria, anti-fungal and

Details Imidazole derivatives and use as anti-bacteria, anti-fungal and Imidazole derivatives and use as anti-bacteria, anti-fungal and

1991-04-03

1992-05-12

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514396, 548335, 548337, A61K 31415, C07D23354

Patent

active

051128446

ABSTRACT:
The synthesis of quaternary five membered N-n-alkyl-heterocycles, especially of 4-hydroxy-N(1)-n-alkyl-imidazolium, 2,5-substituted N(3)-n-alkyl-thiazolium and substituted N(2) pyrazolium salts are described. The N-surfactants obtained have a very small critical micelle concentration (CMC) of 10.sup.-5 -10.sup.-7 Mol/Liter, and are capable of forming micelles of different sizes and forms depending on the nature of the anions. The N-detergents can be used as pharmaceuticals.

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