Imidazole derivatives and their use for modulating the GABA...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S131000, C546S269100, C514S330000

Reexamination Certificate

active

07858649

ABSTRACT:
This invention relates to novel imidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are of the general formula (I) and include any of its stereoisomers, any mixture of its stereoisomers, and pharmaceutically acceptable salts thereof. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAAreceptor complex, and in particular for combating anxiety and related diseases.

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patent: 5179111 (1993-01-01), Biere et al.
patent: 2003/0055085 (2003-03-01), Wagenen et al.
patent: 2006/0217420 (2006-09-01), Cosford et al.
patent: WO 8801268 (1988-02-01), None
patent: 0 323 799 (1989-07-01), None
patent: WO-88/01268 (1988-02-01), None
patent: WO-00/78728 (2000-12-01), None
patent: WO-02/068417 (2002-09-01), None
patent: WO-03/053922 (2003-07-01), None

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