Imidazole derivatives and antimycotics containing them

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

548341, 548336, 546276, 514399, 514397, A61K 31415, C07D23354, C07D40300, C07D40100

Patent

active

049258559

ABSTRACT:
New imidazole derivatives of the formula ##STR1## in which Ar denotes phenyl, biphenylyl, naphthyl or thienyl, each of which is optionally substituted by halogen, lower alkyl or lower alkoxy, R.sub.1 denotes hydrogen or lower alkyl, Alk denotes straight-chain or branched alkylene having 1 to 10 carbon atoms, Y denotes oxygen, sulfur, sulfinyl or sulfonyl, n denotes one of the numbers 0, 1 or 2, Z denotes sulfur or sulfinyl, m denotes the number 0 or 1, m being the number 0 when Y denotes sulfur, sulfinyl or sulfonyl, and m being the number 1 when Y denotes oxygen, and R.sub.2 denotes cyclohexyl, phenyl or naphthyl, each of which is optionally substituted by hydroxyl, halogen, trifluoromethyl, lower alkyl or lower alkoxy, or denotes biphenylyl or pyridyl, and processes for their preparation. The imidazole derivatives have excellent antimycotic properties for use in human and veterinary medicine.

REFERENCES:
patent: 3839574 (1974-10-01), Godefroi et al.
patent: 4559077 (1985-12-01), Regel et al.
patent: 4568687 (1986-02-01), Wright, Jr. et al.
patent: 4623655 (1986-11-01), Gayer et al.
H. Buchel, "The History of Azole Chemistry," 1986, pp. 11-23.
G. Jager, "The Chemistry of N-Substituted Azole Fungicides, "1983, pp. 55-65.
Godefroi et al., J. Med. Chem. 1969, pp. 784-791.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Imidazole derivatives and antimycotics containing them does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Imidazole derivatives and antimycotics containing them, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Imidazole derivatives and antimycotics containing them will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-621757

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.