Imidazole derivatives and a process for the preparation thereof

Details Imidazole derivatives and a process for the preparation thereof Imidazole derivatives and a process for the preparation thereof

1989-05-23

1990-10-23

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548342, C07F 306

Patent

active

049653652

ABSTRACT:
Imidazole derivatives and a process for the preparation thereof.
The imidazole derivatives have remarkable antiulcer properties and are of the following formula: ##STR1## where X is an anion of pharmaceutically acceptable acids; a is 1, 2, 3, 4 or 5; b is 1, 2, 3, 4, 5, 6 or 7; c is 1, 2, 3 or 4; d is twice a minus c; and n is 0, 1, 2 or 3.
The process for the preparation thereof is based on reacting cimetidine and a zinc compound containing the anion X.

REFERENCES:
patent: 4381395 (1983-04-01), Terajii et al.
patent: 4413129 (1983-11-01), Ochikuga et al.

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