Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-08-05
1984-03-06
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
546271, 548309, C07D49114, A61K 3144
Patent
active
044354061
ABSTRACT:
Tricyclic imidazole derivatives of the formula ##STR1## wherein R.sup.1 is 2-pyridyl optionally substituted by lower alkyl or lower alkoxy, n is the integer 0 or 1, R.sup.2 is hydrogen or lower alkyl, R.sup.3 and R.sup.4, independently, are hydrogen or lower alkyl, A is a group of the formula ##STR2## m is the integer 2 or 3, R.sup.5, R.sup.6, R.sup.7 and R.sup.8, independently, are hydrogen or lower alkyl, and R.sup.9 is hydrogen and R.sup.10 is hydrogen or lower alkyl or R.sup.9 and R.sup.10 taken together are oxo, provided that at least one of R.sup.3 and R.sup.4 is lower alkyl when A is a group of the formula
REFERENCES:
patent: 4182766 (1980-08-01), Krasso et al.
Sundell et al., Acta Physiol. Scand. Suppl. 473, (41), 1979.
Krasso Anna
Ramuz Henri
Boxer Matthew
Hoffmann-La Roche Inc.
Leon Bernard S.
Rotman Alan L.
Saxe Jon S.
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