Imidazole derivative tincture and method of manufacture

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

5483411, 5483421, A61K 31415, C07D23360

Patent

active

054610680

ABSTRACT:
A stable solvent system for imidazole derivatives useful in treating antifungal diseases is described. The system comprises a primary carboxylic acid, a polar solvent, a solubilizer, one or more surfactants, and therapeutically effective amounts of an imidazole derivative, preferably miconazole nitrate.

REFERENCES:
patent: 3717655 (1973-02-01), Godefroi et al.
patent: 4912124 (1990-03-01), Das et al.
patent: 5104893 (1992-04-01), Bononi
patent: 5110809 (1992-08-01), Wang et al.

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