Imidazole derivative, pharmaceutically acceptable salt thereof,

Details Imidazole derivative, pharmaceutically acceptable salt thereof, Imidazole derivative, pharmaceutically acceptable salt thereof,

1996-02-20

1998-03-31

Morris, Patricia L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5483201, A61K 31415, C07D23342

Patent

active

057339228

ABSTRACT:
An imidazole derivative represented by one of formulas (1), wherein R.sub.1, R.sub.2 represents hydrogen atom, lower alkyl, aryl, aralkyl group, or R.sub.1 and R.sub.2 cooperate to represent alkylene, alkylidene, arylalkylidene group, R.sub.3 representing hydrogen atom, lower alkyl or alkanoyl group, or aralkyl or arylcarbonyl group, wherein at least one of A and B represents a group represented by formula (2), wherein m represents an integer 1-4, R.sub.4 representing nitrogen-containing aromatic ring that may be substituted by lower alkyl, alkoxy or alkanoyl group, or phenyl group represented by formula (3), R.sub.5, R.sub.6 representing hydrogen atom, lower alkyl or alkenyl group, or lower alkanoyl or arylcarbonyl group which may be substituted by a halogen atom, R.sub.7 representing hydrogen or halogen atom, hydroxyl or nitro group, or lower alkyl or alkoxy group, wherein the other of A and B represents oxygen or sulfur atom, hydroxyl, mercapto, alkylthio, alkenylthio or aralkylthio group, or group represented by the formula (2), ##STR1##

REFERENCES:
patent: 4255431 (1981-03-01), Junggren et al.
patent: 4337257 (1982-06-01), Junggren et al.
patent: 4508905 (1985-04-01), Junggren et al.

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