Imidazole derivative, pharmaceutical use thereof, and intermedia

Details Imidazole derivative, pharmaceutical use thereof, and intermedia Imidazole derivative, pharmaceutical use thereof, and intermedia

1995-02-23

1996-07-23

Bernhardt, Emily

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514254, 514323, 544370, 546201, 5483121, A61K 31495, A61K 31445, C07D40114, C07D40314

Patent

active

055389732

ABSTRACT:
An imidazole derivative of the formula (I) ##STR1## wherein each symbol is as defined in the specification, or a pharmacologically acceptable salt thereof is described. A method for producing the compound or its salt, and its pharmaceutical use, particularly as an agent for the prophylaxis and treatment of the diseases induced by thromboxane A.sub.2 or histamine are described. Also, compounds of the formula (II) and (IV) ##STR2## wherein each symbol is as defined in the specification are described. The imidazole derivative and its parmacologically acceptable salt are useful as agents for the prophylaxis and treatment of the diseases induced by thromboxane A.sub.2 or histamine, and the intermediate compounds (II) and (IV) are novel compounds.

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