Imidazole compounds useful in radiotherapy or chemotherapy and c

Details Imidazole compounds useful in radiotherapy or chemotherapy and c Imidazole compounds useful in radiotherapy or chemotherapy and c

1985-10-28

1986-06-24

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548336, A61K 31415, C07D40306

Patent

active

045968179

ABSTRACT:
A chemopotentiating or radiation sensitizing compound of formula I ##STR1## in which formula: R.sub.1 represents hydrogen or an alkyl group;

REFERENCES:
patent: 4241060 (1980-12-01), Smithen
patent: 4282232 (1981-08-01), Agrawal
Cancer-vol. 48, No. 3, Aug. 1, 1981-American Cancer Society, Inc. J. P. Lippincott Company,-696-707.
Hypoxia Mediated Radiation and Chemo-Sensitizing Drugs Br. J. Cancer (1984), 50, 285-289.
Radiation Sensitization and Chemopotentiation; RSU 1069, A Compound more Efficient than Misonidazole-Br.J. Cancer (1984) 49, 571-577.
Stratford, Int. J. Radiation Biol. Phys., vol. 8, 391-392 (1982).
Smithen et al., Chemical Abstracts, vol. 95 (1981) No. 17999S.

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