Imidazole compounds as anti-inflammatory and analgesic agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S341000, C514S365000, C514S393000, C546S275100, C546S274100, C548S331500, C548S343500, C548S202000, C548S302700

Reexamination Certificate

active

06956050

ABSTRACT:
This invention provides a compound of the formula (I):wherein:R1represents a hydrogen atom, an alkyl group, etc.; R2represents a hydrogen atom, a halogen atom, etc.; R3represents a hydrogen atom, an alkyl group, etc.; R4represents an aryl group, etc.; A represents an aryl1, etc; B represents an alkylene etc.; X represents NH, etc.;or a pharmaceutically acceptable ester of such compound, and pharmaceutically acceptable salts thereof.These compounds are useful for the treatment of medical conditions mediated by prostaglamndin such as pain, fever or inflammation, etc. This invention also provides a pharmaceutical composition comprising the above compound.

REFERENCES:
patent: 1 122 243 (1999-10-01), None
patent: WO 97/22341 (1997-06-01), None
patent: WO-9722341 (1997-06-01), None
patent: WO 99/47497 (1999-09-01), None
patent: WO 00/64888 (2000-11-01), None
patent: WO 02/32422 (2002-04-01), None

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