Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1990-10-01
1992-06-30
Morris, Patricia L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514396, 514397, 514398, 514399, 514400, 544139, 548335, 548336, 548337, 548338, 548339, 548340, 548342, 548343, 548346, A61K 31415, A61K 31535, C07D23393, C07D23390
Patent
active
051263424
ABSTRACT:
There are disclosed substituted imidazole derivatives of Formula I which are useful as angiotensin II antagonists. ##STR1##
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Bolis et al., J. Med. Chem., 30, 1729-1737 (1987).
Burger, A., Medicinal Chemistry, 2nd Ed., Interscience Pub., N.Y., pp. 565-571, 578-581, 600-601 (1960).
Denkewalter et al., Progress in Drug Research, vol. 10, 510-512 (1966).
Haber et al., J. Cardiovascular Pharmacology, 10, Suppl. S54-S58 (1987).
Plattner et al., J. Med. Chem., 31, 2277-2288 (1988).
Chakravarty Prasun K.
Greenlee William J.
Naylor Elizabeth M.
Patchett Arthur A.
Walsh Thomas F.
DiPrima Joseph F.
Merck & Co. , Inc.
Miltenberger Lenora
Morris Patricia L.
Nicholson William H.
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