Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-11-28
1996-08-13
Davis, Zinna Northington
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5142358, 514307, 514314, 514326, 514333, 514341, 514359, 514383, 514397, 514398, 514399, 514400, 544139, 546148, 546174, 546176, 546180, 546210, 546256, 5462724, 5462727, 5462744, 5462747, 5462751, 546 22, 546 23, 546 24, 548253, 548255, 548261, 5482662, 5483151, 5483351, 5483411, 5483431, 5483435, 5483461, 5483147, C07D40114, A61K 31415
Patent
active
055456510
ABSTRACT:
Novel substituted imidazoles of Formula (I), which are useful as angiotensin II antagonists, are disclosed: ##STR1##
REFERENCES:
patent: 5138069 (1992-08-01), Carini et al.
P. C. Wong, et al., Cardiovascular Drug Reviews 1991; 9:317-339; Trends in Endocrinol. Metal. 1992; 3:211-217).
Carini et al, J. Med. Chem, vol. 34, No. 8, 1991, pp. 2525-2547.
Chiu et al, Biochem. Biophys. Res. Comm, vol. 188, No. 3, Nov. 16, 1992, pp. 1030-1039.
Duncia John J. V.
Ensinger Carol L.
Olson Richard E.
Quan Mimi L.
Santella III Joseph B.
Davis Zinna Northington
The DuPont Merck Pharmaceutical Company
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