Imidazoindole derivatives and pharmaceutical compositions compri

Details Imidazoindole derivatives and pharmaceutical compositions compri Imidazoindole derivatives and pharmaceutical compositions compri

1979-03-29

1981-03-10

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

424251, 544281, 544330, 546304, 546 64, 546121, A61K 31505, C07D48714

Patent

active

042555736

ABSTRACT:
Pharmaceutical composition for chelating excess iron in a mammal and facilitating the removal of excess iron from the mammalian body are disclosed which comprise as active ingredient an iron-chelating agent selected from the group consisting of 5H-pyrimido(2',1':2,3)imidazo(4,5-b)indole having the formula ##STR1## 5H-pyrido(2',1':2,3)imidazo(4,5-b) indole having the formula ##STR2## or lower alkyl and/or halogen substituted derivatives thereof and pharmaceutically acceptable acid addition salts thereof. Furthermore the preparation of novel 5H-pyrimido(2',1':2,3)imidazo(4,5-b)indoles and intermediates thereof are disclosed.

REFERENCES:
patent: 2556574 (1951-06-01), Cambell et al.
patent: 3108108 (1963-10-01), Schellhammer et al.

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