Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-01-16
1997-09-09
Bond, Robert T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540499, 540498, A61K 31555, C07D521000
Patent
active
056657188
ABSTRACT:
The invention relates to compounds of the formula ##STR1## wherein A together with the two carbon atoms denoted by .alpha. and .beta. is one of the residues ##STR2## Q is one of the residues ##STR3## R.sup.1 and R.sup.2 each independently are hydrogen, lower alkyl, lower alkenyl, lower alkynyl, lower hydroxyalkyl, lower alkoxy-lower alkyl, (C.sub.3 -C.sub.6)-cycloalkyl, (C.sub.3 -C.sub.6)-cycloalkyl-lower alkyl, amino-lower alkyl, lower alkylamino-lower alkyl, di-lower alkylamino-lower alkyl or aryl-lower alkyl or together with the nitrogen atom are a 5- to 8-membered membered heterocycle optionally containing a further hetero atom or a fused benzene ring,
REFERENCES:
patent: 4507313 (1985-03-01), Braestrup et al.
patent: 4622321 (1986-11-01), Watjen et al.
patent: 4670433 (1987-06-01), Watjen et al.
patent: 4772599 (1988-09-01), Watjen et al.
patent: 4775671 (1988-10-01), Hunkeler et al.
patent: 4886797 (1989-12-01), Watjen et al.
patent: 4904654 (1990-02-01), Lin et al.
patent: 4939139 (1990-07-01), Lin et al.
Israel abridgment of 74070 pp. 2216-2217 (Jan. 16, 1985).
Israel abridgment of 82117 p. 330 (Apr. 6, 1987).
Nature 294, pp. 763-765 (1981).
J. Neurochemistry 37, pp. 714-722 (1981).
Journal of Medicinal Chemistry vol.32, No. 10, pp. 2282-2291 (Oct. 1989).
Research Communications In Chemical Pathology & Pharmacology, vol. 80, No. 3, pp. 357-362 (Jun. 1993).
Journal of Medicinal Chemistry vol. 36, No. 4, pp. 479-490 (Feb. 19, 1993).
Advances In Biochemical Psychopharmacology vol. 45, pp. 209-217 (1988).
Godel Thierry
Hunkeler Walter
Stadler Heinz
Widmer Ulrich
Bond Robert T.
Ciambrone Coletti Ellen
Hoffmann-La Roche Inc.
Johnston George W.
Silverman Robert A.
LandOfFree
Imidazodiazepines does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Imidazodiazepines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Imidazodiazepines will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-70115