Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-02-28
2006-02-28
Balasubramanian, Venkataraman (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S184000
Reexamination Certificate
active
07005431
ABSTRACT:
A class of 7-phenylimidazo[1,2-b][1,2,4]triazine derivatives, substituted at the meta position of the phenyl ring by an optionally substituted aryl or heteroaryl group which is directly attached or bridged by an oxygen atom or a —NH— linkage, and substituted on the phenyl ring by one or two further substituents as defined herein, being selective ligands for GABAAreceptors, in particular having good affinity for the α2 and/or α3 and/or α5 subunit thereof, are accordingly of benefit in the treatment and/or prevention of adverse conditions of the central nervous system, including anxiety, convulsions and cognitive disorders.
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patent: WO 00 23449 (2000-04-01), None
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Scott et al. Prog. Med. Chem. 36: 169-200,1999.
Bettati Michela
Chambers Mark Stuart
Goodacre Simon Charles
Hallett David James
Russell Michael Geoffrey Neil
Balasubramanian Venkataraman
Merck Sharp & Dohme Ltd.
Thies J. Eric
Winokur Melvin
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