Imidazo [4,5-B] pyridine compounds and their pharmaceuticals...

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

Reexamination Certificate

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Details

C544S324000, C544S331000, C514S234200, C514S236200, C514S252160, C514S275000

Reexamination Certificate

active

06891039

ABSTRACT:
Compounds of formula (I)and pharmaceutically-acceptable and pharmaceutically-acceptable and -cleavable esters thereof and acid addition salts thereof, wherein the symbols are as defined are MAP kinase inhibitors, useful pharmaceutically for treating TNFα and IL-1 mediated diseases such as rheumatoid arthritis and diseases of bone metabolism, e.g. osteoporosis.

REFERENCES:
patent: 5739143 (1998-04-01), Adams et al.
patent: 9513067 (1995-05-01), None
patent: 9705878 (1997-02-01), None
patent: 9921555 (1999-05-01), None
patent: 0009506 (2000-02-01), None
patent: 0063204 (2000-10-01), None
patent: 0064894 (2000-11-01), None
patent: 0069848 (2000-11-01), None
Rasmussen, PubMed Abstract, Dan Med Bull, vol. 47, No. 2, pp. 94-114 (2000).

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