Imidazo[4,5-b]pyridine compounds and pharmaceutical compositions

Details Imidazo[4,5-b]pyridine compounds and pharmaceutical compositions Imidazo[4,5-b]pyridine compounds and pharmaceutical compositions

1987-07-24

1989-02-28

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546118, A61K 31435, C07D47104

Patent

active

048085960

ABSTRACT:
Imidazo[4,5-b]pyridine compounds of the general formula [I] are provided: ##STR1## where R.sup.1 is straight-chain or branched C.sub.1-8 alkoxy which may be substituted with cycloalkyl, or C.sub.2-4 fluoroalkyloxy, R.sup.2 is H, methyl or methoxy, and R.sup.3 and R.sup.4 are each H or methyl and may be the same or different. All these compounds have good activity of inhibiting potassium ion-dependent adenosine triphosphatase and excellent storage stability, so that they are usable for the treatment of gastric and/or duodenal ulcers.

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