Imidazo[2,2-b][3]benzazepine and pyrimido[2,1-b][3]benzazepine a

Details Imidazo[2,2-b][3]benzazepine and pyrimido[2,1-b][3]benzazepine a Imidazo[2,2-b][3]benzazepine and pyrimido[2,1-b][3]benzazepine a

1991-09-10

1992-04-21

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540551, A61K 3155, C07D48704

Patent

active

051068443

ABSTRACT:
Novel imidazo[2,1-b][3]benzazepines and pyrimido[2,1-b][3]benzazepines of formula I, pharmaceutical compositions containing them, methods for treating cardiac arrhythmia in mammals utilizing them, and processes for synthesizing them. ##STR1##

REFERENCES:
Johnson et al., "J. Het. Chem", vol. 2, No. 1, pp. 26-36 (1965).
Wendelin, W. et al., "Bridged Derivatives of Phenylethylamines and Nitrogen Analogous Compounds. Part 2. Synthesis and Pharmacological Activities of 4-5-Dihydro-1H-3-Benzazepines and Fused Derivatives" Sci. Pharm. 57:27-38 (1989).
Vejdelek, Z. and Protiva, M., "Synthesis of Some Derivatives of 1-Phenyl-2,3,4,5-Tetrahydro-1H-3-Benzazepine and 11-Phenyl-5,6-Dihydro-11H-S-Triazolo[3,4-b]-3-Benzazepine" Collect. Czech. Chem. Commun. 55:2345-2350 (1990).

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