Imidazo[1,2-]pyridazines for cortical cholinergic deficiencies

Details Imidazo[1,2-]pyridazines for cortical cholinergic deficiencies Imidazo[1,2-]pyridazines for cortical cholinergic deficiencies

1988-08-31

1990-03-20

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514248, 544117, A61K 3150, C07D47100

Patent

active

049101994

ABSTRACT:
The present invention relates to imidazo[1,2-b]-pyridazines having the formula: ##STR1## in which: R.sub.1 represents hydrogen, a halogen atom, a C.sub.1 -C.sub.4 alkoxy group or a C.sub.1 -C.sub.4 alkyl group occupying one of the free positions of the benzene ring; R.sub.2 represents hydrogen, a C.sub.1 -C.sub.4 alkyl group or a phenyl group; R.sub.3 denotes hydrogen, a C.sub.1 -C.sub.4 alkyl group or a phenyl group; and R.sub.4 R.sub.5 represent hydrogen or a C.sub.1 -C.sub.4 alkyl group, or R.sub.4 and R.sub.5 form, together with the nitrogen atom to which they are bonded, a 5-membered or 6-membered heterocycle optionally containing a second heteroatom. Application: drugs, especially for the treatment of cortical cholinergic deficiencies.

REFERENCES:
patent: 3489755 (1970-01-01), Lombardino
patent: 3828041 (1974-08-01), Tomcufcik
patent: 4353903 (1982-10-01), Fabiani
patent: 4464372 (1984-08-01), Bristol

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